Almost one year ago, the ICH published its Guideline for Residual Solvents in the version ICH Q3C (R6) introducing new PDE-Levels for Triethylamine and Methylisobutylketone.
Currently, this Guideline is again undergoing maintenance, which shall result in the future Q3C(R7) version, to develop PDE levels for the following three solvents:

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